Pre-term Labour Markers

Pre-term delivery is a serious complication of pregnancy and several markers are used to assess the risk of pre-term delivery.

The Weqas Pre-term Labour Marker (PTLM) suite of programmes were launched in February 2013, starting with Foetal Fibronectin and then the further additions of phosphorylated IGFBP-1 and IGFBP-1 programmes. Separate programmes are provided for Foetal Fibronectin, phosphorylated IGFBP-1 and IGFBP-1. All are accredited to ISO 17043 (UKAS accredited testing laboratory no.4301)

Foetal Fibronectin (fFN)
Frequency: Bimonthly
Samples: 2 (0.6 mL)
Material: Synthetic Amniotic Fluid containing purified fFN

Key features: Liquid stable samples are supplied ready to use; no pre-analytical preparation is required. Qualitative and Quantitative reporting available, with interpretations based on cut-offs of 50 and 200 ng/mL (EQUiPP study 2014). Linear related panel distributed covering the clinically relevant range. Programme assesses both site and device performance, including bias, within and between batch imprecision and linearity.

phIGFBP-1
Frequency: Bimonthly
Samples: 2 (1.0 mL)
Material: Synthetic Amniotic Fluid containing semi-purified IGFBP-1

Key features: Liquid stable samples are supplied ready to use; no pre-analytical preparation is required. Linear related panel distributed covering the clinically relevant range. Programme assesses both site and device performance, including bias, within and between batch imprecision and linearity.

IGFBP-1
Frequency: Bimonthly
Samples: 2 (1.0 mL)
Material: Synthetic Amniotic Fluid containing semi-purified IGFBP-1

Pre Term Labour Marker Programme
Analyte	Approx. Range Covered
Quantitative fFN	0 - 400	ng/ml
Qualitative fFN	Negative / Positive
phIGFBP-1	Negative / Positive
IGFBP-1	Negative / Positive