Homocysteine is tested as part of a “cardiac risk assessment” and is also used to determine folate-deficiency or vitamin B12-deficiency as blood homocysteine concentration can be raised in both conditions.

Three liquid human serum samples covering a range of concentrations including both Inborn errors and Cardiac range are distributed on a bi-monthly basis. Challenging sample from patients with known homocysteinuria are distributed, commutable across all testing platforms. Occasionally donations from healthy volunteers may be spiked with an exogenous source to enhance the pathological range.  Values assigned by HPLC method provided.

Frequency: Bimonthly

Samples per set: 3 x 0.5mL

Homocysteine Programme
AnalyteApprox. Range Covered
Homocysteine 5 - 140 µmol/L

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